Full name: Biomarkers for RAtional Investigation for Neurological decision Support in TBI: BRaINS-TBI
PI: Dr Virginia Newcombe
Study start and end dates: January 2025 to December 2028
Funder: NIHR EME (Award ID: NIHR159241)
Summary: BRAINS-TBI is a cohort study of 2048 patients with embedded RCT of ~800 patients who present to 10 UK Emergency Departments after sustaining a mild traumatic brain injury. It aims to answer two key questions: 1) Can blood biomarkers reduce the number of CT scans performed in the ED for mild TBI? 2) Can Biomarkers identify patients at higher risk of long-term problems following mild TBI? Health economic and Communication of Risk work packages are planned. Findings in adults will be tested in a paediatric cohort being recruited separately at Alder Hey Hospital, Liverpool.