Welcome to TBI-REPORTER
UK TBI-Repository and Data Portal Enabling Discovery
Traumatic Brain Injury (TBI) is a major cause of death and disability. In the UK alone, TBI care costs over £10 billion each year and globally it costs over $400 billion. TBI can lead to long-term health issues such as dementia, epilepsy, mental health problems, and a shorter lifespan. While we have gained some understanding of the underlying processes driving TBI related health outcomes, drug trials have often failed and progress in clinical care has been slow. However, over the years, each of the individual studies investigating TBI and its outcomes has gathered potentially very informative data that, to date, has not been widely available to researchers outside of the original studies.
Learn about what PPIE is and how to use it.
Read more about our program governance documents and meeting notes.
Meet our amazing team.
Learn about what PPIE is and how to use it.
Read more about our program governance documents and meeting notes.
Meet our amazing team.
To address this, we are creating a research platform called The UK-TBI REpository and data PORTal Enabling discoveRy (TBI-REPORTER). This exciting MRC/NIHR/MoD/ARUK funded initiative will bring together existing TBI research data and samples gathered in past and ongoing research programs in the UK and make it more accessible to scientists. TBI-REPORTER will also establish a network of centres across the UK to support clinical trials of novel treatments.
By doing so, we hope to aid the development of new diagnostic techniques, therapeutic interventions, and personalized treatments for TBI. TBI-REPORTER will cover all age groups, including children and older adults, as well as particular groups like military personnel, athletes, prisoners, homeless individuals, and victims of domestic violence.
The data in TBI-REPORTER will be available to researchers from the UK and around the world. This will speed up TBI research and improve our understanding of its lifelong impact on health, leading to better treatment and individualized care.
TBI-REPORTER consists of a consortium of leading UK investigators and stakeholders and will establish a robust and sustainable platform to facilitate research in TBI across the lifespan.
Latest News
Analytical Validation of Minimally Invasive Capillary Blood Microsampling using Tasso+ for Multiplexed Neurological Biomarkers.
Owen Swann, Sophie Hicks, Caleigh Lynch, Amie Wallman-Jones, Maryam Shoai, Rachel Mulvaney, Bárbara Fernandes Gomes, Eleftheria Kodosaki, Margherita Tecilla, Mazdak Ghajari, Ben Jones, Simon Kemp, TBI-REPORTER Biomarker Group, Richard Sylvester, Matt Cross, Keith Stokes, Mathew G Wilson, David K Menon, Amanda Heslegrave, Henrik Zetterberg, David J Sharp, Thomas D Parker.
Days alive and out of hospital after burr-hole drainage for chronic subdural haematoma: a national cohort study using Hospital Episode Statistics in England.
Thompson D, Wahba A, Davies B, et al.
The microdialysis-derived lactate–pyruvate gradient indicates anaerobic activity after brain injury.
Baker MS, Heihre JM, Kuliński TB, Smith CA, Barlas B, Zimphango C, Timofeev I, Baranes K, Carpenter KLH, Kotter M,